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CEFTIFLEX® (ceftiofur sodium sterile powder) contains the sodium salt of ceftiofur which is a broad spectrum cephalosporin antibiotic active against gram-positive and gram-negative bacteria including β-lactamase-producing strains. Like other cephalosporins, ceftiofur is bactericidal in vitro, resulting from inhibition of cell wall synthesis.
Highly Effective CEFTIFLEX® is indicated for treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. Ceftiofur sodium has also shown to be effective against Streptococcus equi, Rhodococcus equi, Bacteroides spp., and Fusobacterium necrophorum.
Easy to Use CEFTIFLEX® should be administered to horses by intramuscular injection at the dosage of 1.0 to 2.0 mg ceftiofur per pound (2.2 to 4.4 mg/kg) of body weight (2-4mL reconstituted sterile solution per 100 lbs body weight). A maximum of 10 mL may be administered per injection site. Treatment should be repeated at 24-hour intervals, continued for 48 hours after clinical signs have disappeared and should not exceed 10 days.
Wide Margin of Safety Ceftiofur sodium was well tolerated when administered intramuscularly to male and female horses at doses up to 5.0 mg/lb/day for 30 or 31 days. No clinical evidence of irritation was noted at any dose. The safety of ceftiofur has not been determined for horses intended for breeding.
Each mL of the reconstituted drug contains ceftiofur sodium equivalent to 50 mg ceftiofur. The pH was adjusted with sodium hydroxide and monobasic potassium phosphate.
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
KEEP OUT OF REACH OF CHILDREN
FOR ANIMAL USE ONLY
CEFTIFLEX® Re-hydration procedure video.
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